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Interestingly, however, the lack of mitotic figures does not necessarily indicate a more benign course of the disease

J Clin Endocrinol Metab (2008) 93:120310.10.1210/jc.2007-1986 28 TaboadaGFLuqueRMNetoLVMachado EdeOSbaffiBCDominguesRCet alQuantitative analysis of somatostatin receptor subtypes (1-5) gene expression levels in somatotropinomas and correlation to in vivo hormonal and tumor volume responses to treatment with octreotide LAR

FGR can be caused by placental insufficiency, which can lower levels of fetal insulin-like growth factor 1 (IGF-1) and insulin, both of which are critical for growth

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